Serum beta-glucuronidase activity in response to fruit and vegetable supplementation: a controlled feeding study.

Publication Type:

Journal Article


Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Volume 17, Issue 7, p.1808-12 (2008)


2008, Adult, Center-Authored Paper, Cross-Over Studies, Dietary Supplements, Female, Follow-Up Studies, Fruit, Glucuronidase, Humans, Incidence, Male, Neoplasms, Prevention Center Core Facility, Public Health Sciences Division, Risk Factors, Shared Resources, Specialized Pathology Core Facility, Spectrophotometry, Vaccine and Infectious Disease Institute, Vegetables, Washington, Young Adult


Fruit and vegetable (F&V) intake may lower the risk of some cancers. One hypothesized, but understudied, chemopreventive mechanism is that plant food constituents inhibit beta-glucuronidase, an acid hydrolase that deconjugates glucuronides.