Self Collection of Foam Nasal Swabs for Respiratory Virus Detection by PCR among Immunocompetent Subjects and Hematopoietic Cell Transplant Recipients.

Publication Type:

Journal Article

Source:

Journal of clinical microbiology, Volume 51, Issue 1, p.324-327 (2013)

Keywords:

2013, Center-Authored Paper, Clinical Research Division, November 2012, Public Health Sciences Division, Vaccine and Infectious Disease Division

Abstract:

Self-collected foam nasal swabs (NS) obtained after instillation of saline spray were compared with nasal washes from immunocompetent subjects during 146 upper respiratory infections (URIs); sensitivity for RT-PCR respiratory virus detection was 95% and 88%, respectively (p=0.06). Sensitivities from NS collected with and without saline spray during 142 URIs from immunocompetent subjects were 96% and 86% (p=0.004), and from 140 URI samples from hematopoietic cell transplantation recipients were 88% and 85% (p=0.56), respectively.