Scientific Advances in Lung Cancer 2015.

Publication Type:

Journal Article


Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer (2016)


Lung cancer continues to be a major global health problem with more than 1.6 million new patients diagnosed each year with this disease. However, significant progress is underway in both the prevention and treatment of lung cancer. Lung cancer therapy has now emerged as a "role model" for precision cancer medicine with several important therapeutic breakthroughs occurring during 2015. These advances have occurred primarily in the immunotherapy field and in treatments directed against tumors harboring specific oncogenic drivers. Our knowledge about molecular mechanisms for oncogenic driven tumors and about resistance to targeted therapies has increased quickly over the last year. As a result, several regulatory approvals of new agents have occurred; which significantly improve survival and quality of life for lung cancer patients with advanced disease. The International Association for the Study of Lung Cancer has gathered experts in different areas of lung cancer research and management to summarize the most significant scientific advancements related to prevention and therapy of lung cancer during the last year.