Risk of merkel cell carcinoma after solid organ transplantation.

Publication Type:

Journal Article

Source:

Journal of the National Cancer Institute, Volume 107, Issue 2 (2015)

Keywords:

Adult, Aged, Azathioprine, Carcinoma, Merkel Cell, Cyclosporine, Epidemiology Core Facility, Female, Humans, Immunocompromised Host, Immunosuppressive Agents, Incidence, Male, Middle Aged, Organ Transplantation, Photosensitizing Agents, Poisson Distribution, Registries, Remission Induction, Risk Assessment, Risk Factors, Skin Neoplasms, TOR Serine-Threonine Kinases, Transplant Recipients, Ultraviolet Rays, United States

Abstract:

Solid organ transplant recipients have elevated risks of virus-related cancers, in part because of long-term immunosuppression. Merkel cell carcinoma (MCC) is an aggressive skin cancer recently found to have a viral origin, but little is known regarding the occurrence of MCC after transplant.