Risk of human papillomavirus-associated cancers among persons with AIDS.

Publication Type:

Journal Article

Authors:

Chaturvedi, Anil K; Madeleine, Margaret M; Biggar, Robert J; Engels, Eric A

Source:

Journal of the National Cancer Institute, Volume 101, Issue 16, p.1120-30 (2009)

Keywords:

2009, Acquired Immunodeficiency Syndrome, Adult, Aged, Alphapapillomavirus, Antiretroviral Therapy, Highly Active, Anus Neoplasms, CD4 Lymphocyte Count, CD4-Positive T-Lymphocytes, Center-Authored Paper, Female, HIV Infections, Humans, Immunocompromised Host, Incidence, Male, Middle Aged, Neoplasms, Oropharyngeal Neoplasms, Papillomavirus Infections, Penile Neoplasms, Poisson Distribution, Public Health Sciences Division, Research Design, Retrospective Studies, Risk Assessment, Risk Factors, Time Factors, Tumor Virus Infections, United States, Uterine Cervical Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms

Abstract:

Although risk of human papillomavirus (HPV)-associated cancers of the anus, cervix, oropharynx, penis, vagina, and vulva is increased among persons with AIDS, the etiologic role of immunosuppression is unclear and incidence trends for these cancers over time, particularly after the introduction of highly active antiretroviral therapy in 1996, are not well described.