Risk factors for colorectal cancer in patients with multiple serrated polyps: a cross-sectional case series from genetics clinics.

Publication Type:

Journal Article


PloS one, Volume 5, Issue 7, p.e11636 (2010)


2010, Adult, Aged, Center-Authored Paper, Colonic Polyps, Colorectal Neoplasms, Female, Humans, Logistic Models, Male, Middle Aged, Odds Ratio, Public Health Sciences Division, Risk Factors, Sex Factors, Smoking


Patients with multiple serrated polyps are at an increased risk for developing colorectal cancer (CRC). Recent reports have linked cigarette smoking with the subset of CRC that develops from serrated polyps. The aim of this work therefore was to investigate the association between smoking and the risk of CRC in high-risk genetics clinic patients presenting with multiple serrated polyps.