Renal failure does not preclude cure in children receiving chemotherapy for Wilms tumor: a report from the National Wilms Tumor Study Group.

Publication Type:

Journal Article

Authors:

Feusner, James H; Ritchey, Michael L; Norkool, Pat A; Takashima, Janice R; Breslow, Norman E; Green, Daniel M

Source:

Pediatric blood & cancer, Volume 50, Issue 2, p.242-5 (2008)

Keywords:

2008, Antineoplastic Combined Chemotherapy Protocols, Center-Authored Paper, Child, Child, Preschool, Cisplatin, Collaborative Data Services Core Facility, Dactinomycin, Dose-Response Relationship, Drug, Doxorubicin, Etoposide, Female, Humans, Ifosfamide, Infant, Kidney Neoplasms, Male, Public Health Sciences Division, Renal Insufficiency, Shared Resources, Treatment Outcome, Vincristine, Wilms Tumor

Abstract:

Children with Wilms tumor can develop renal failure during treatment. Since there are few published data concerning the appropriate chemotherapy for this situation, we reviewed the experience of children who developed renal failure while being treated on National Wilms Tumor Study Group (NWTSG) studies 1-4 (1969-1994).