Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition.

Publication Type:

Journal Article

Authors:

Bendoraite, Ausra; Knouf, Emily C; Garg, Kavita S; Parkin, Rachael K; Kroh, Evan M; O'Briant, Kathy C; Ventura, Aviva P; Godwin, Andrew K; Karlan, Beth Y; Drescher, Charles W; Urban, Nicole; Knudsen, Beatrice S; Tewari, Muneesh

Source:

Gynecologic oncology, Volume 116, Issue 1, p.117-25 (2010)

Keywords:

2010, Cell Transformation, Neoplastic, Center-Authored Paper, Clinical Research Division, Epithelial Cells, EPITHELIUM, Experimental Histopathology Core Facility, Female, Gene Expression Regulation, Neoplastic, Genomics Core Facility, Homeodomain Proteins, Human Biology Division, Humans, MICRORNAS, Ovarian Neoplasms, Public Health Sciences Division, Repressor Proteins, Reverse Transcriptase Polymerase Chain Reaction, Shared Resources, TRANSCRIPTION FACTORS

Abstract:

Our objective was to characterize the expression and function of the miR-200 family of microRNAs (miRNA) in ovarian carcinogenesis.

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