Red blood cell delta15N: a novel biomarker of dietary eicosapentaenoic acid and docosahexaenoic acid intake.

Publication Type:

Journal Article


The American journal of clinical nutrition, Volume 89, Issue 3, p.913-9 (2009)


2009, Adult, Age Factors, Alaska, Biological Markers, Center-Authored Paper, Cross-Sectional Studies, Dietary Fats, Docosahexaenoic Acids, Eicosapentaenoic Acid, Erythrocytes, Female, Humans, Inuits, Linear Models, Male, Middle Aged, Nitrogen Isotopes, Nutrition Assessment Core Facility, Public Health Sciences Division, Sex Factors, Shared Resources, Young Adult


The long-chain omega-3 (n-3) fatty acids derived from fish, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are associated with a reduced risk of cardiovascular disease and other chronic diseases. Study of the associations between EPA and DHA intake and disease requires a valid biomarker of dietary intake; however, the direct measurement of tissue fatty acid concentrations is expensive and time consuming.