A randomized, double-blind, placebo-controlled Phase II extended safety study of two Invisible Condom formulations in Cameroonian women.

Publication Type:

Journal Article

Source:

Contraception, Volume 81, Issue 1, p.79-85 (2010)

Keywords:

2010, Administration, Intravaginal, Adolescent, Adult, Anti-HIV Agents, Anti-Infective Agents, Local, Cameroon, Center-Authored Paper, Double-Blind Method, Female, HIV Infections, Humans, Middle Aged, Patient Compliance, Patient Satisfaction, Patient Selection, Polymers, Vaccine and Infectious Disease Division, Vaginal Creams, Foams, and Jellies

Abstract:

Invisible Condom gel formulations being developed as microbicides to prevent the sexual transmission of HIV are advancing through the phases of clinical trials. The objectives of this study were to evaluate, after 8 weeks of vaginal application, the extended safety and acceptability of two Invisible Condom vaginal gel formulations: (i) the polymer alone and (ii) the polymer containing sodium lauryl sulfate (SLS) compared to placebo.