A randomized controlled trial comparing the effects of counseling and alarm device on HAART adherence and virologic outcomes.

Publication Type:

Journal Article


PLoS medicine, Volume 8, Issue 3, p.e1000422 (2011)


2011, Adult, Anti-Retroviral Agents, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Counseling, Drug Combinations, Female, HIV Infections, HIV-1, Human Biology Division, Humans, KENYA, Male, Memory, Patient Compliance, Proportional Hazards Models, Public Health Sciences Division, Reminder Systems, RNA, Viral, Treatment Outcome


Behavioral interventions that promote adherence to antiretroviral medications may decrease HIV treatment failure. Antiretroviral treatment programs in sub-Saharan Africa confront increasing financial constraints to provide comprehensive HIV care, which include adherence interventions. This study compared the impact of counseling and use of an alarm device on adherence and biological outcomes in a resource-limited setting.