Radiation monotherapy as regional treatment for lymph node-positive Merkel cell carcinoma.

Publication Type:

Journal Article


Cancer, Volume 116, Issue 7, p.1783-90 (2010)


2010, Aged, Aged, 80 and over, Carcinoma, Merkel Cell, Center-Authored Paper, Clinical Research Division, Female, Humans, Lymph Node Excision, Lymphatic Metastasis, Male, Middle Aged, RECURRENCE, Sentinel Lymph Node Biopsy, Skin Neoplasms, Treatment Outcome


: Merkel cell carcinoma (MCC) is an aggressive cutaneous malignancy with a high risk of lymph node involvement. To the authors' knowledge, few data have been published to date regarding the optimal regional therapy for lymph node-positive patients. This cohort study was performed to analyze the outcomes of patients with lymph node-positive MCC treated with lymph node irradiation as definitive therapy compared with completion lymphadenectomy (CLND).