Quantitative assessment of the role of male circumcision in HIV epidemiology at the population level.

Publication Type:

Journal Article


Epidemics, Volume 1, Issue 3, p.139-52 (2009)


2009, Adolescent, Adult, Africa South of the Sahara, Center-Authored Paper, Circumcision, Male, Female, HIV Infections, Humans, Linear Models, Male, Middle Aged, Prevalence, Randomized Controlled Trials as Topic, Risk-Taking, Vaccine and Infectious Disease Institute, Young Adult


Three recent randomized trials have shown that male circumcision (circumcision) reduces HIV incidence in heterosexual men by about 60%. Mathematical models are needed to assess the historical role of circumcision in the observed disparate levels of prevalence in sub-Saharan Africa and to translate these findings into estimates of the population-level impact of circumcision on HIV prevalence.