Quantification of population benefit in evaluation of biomarkers: practical implications for disease detection and prevention.

Publication Type:

Journal Article


BMC medical informatics and decision making, Volume 14, Issue 1, p.15 (2014)


2014, Center-Authored Paper, Human Biology Division, March 2014, Public Health Sciences Division


With the rapid development of "-omic" technologies, an increasing number of purported biomarkers have been identified for cancer and other diseases. The process of identifying those that are most promising and validating them for use at the population level for prevention and early detection is a critical next step in achieving significant health benefits.