Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.

Publication Type:

Journal Article

Source:

PloS one, Volume 9, Issue 12, p.e113203 (2014)

Keywords:

2014, Scientific Imaging Core Facility, Shared Resources

Abstract:

Coronary heart disease (CHD) is a leading cause of morbidity and mortality in African Americans. However, there is a paucity of studies assessing genetic determinants of CHD in African Americans. We examined the association of published variants in CHD loci with incident CHD, attempted to fine map these loci, and characterize novel variants influencing CHD risk in African Americans.