Principles of peripheral blood mononuclear cell apheresis in a preclinical canine model of hematopoietic cell transplantation.

Publication Type:

Journal Article

Source:

Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, Volume 22, Issue 1, p.74-82 (2008)

Keywords:

2008, Age Distribution, Animals, Blood Cell Count, Body Weight, Cell Processing Core Facility, Center-Authored Paper, Clinical Research Division, Comparative Medicine Core Facility, Dogs, Experimental Histopathology Core Facility, Female, Granulocyte Colony-Stimulating Factor, hematopoietic stem cell transplantation, Leukapheresis, Leukocytes, Mononuclear, Male, Research Trials Office Core Facility - Biostatistics Service, Retrospective Studies, Sex Characteristics, Shared Resources

Abstract:

Preclinical studies of peripheral blood mononuclear cell (PBMC) transplantation conducted in a well-established canine hematopoietic cell transplantation (HCT) model have been successfully translated to human patients over the past 5 decades.