Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer.

Publication Type:

Journal Article


Journal for immunotherapy of cancer, Volume 3, p.16 (2015)


Translational Bioimaging Center Core Facility


Ovarian cancer is immunogenic and residual tumor volume after surgery is known to be prognostic. Ovarian cancer often follows a recurring-remitting course and microscopic disease states may present ideal opportunities for immune therapies. We sought to establish the immune profile of a murine model of ovarian cancer that allows in vivo tumor imaging and the quantitation of microscopic disease.