Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer.

Publication Type:

Journal Article

Source:

Journal for immunotherapy of cancer, Volume 3, p.16 (2015)

Keywords:

Translational Bioimaging Center Core Facility

Abstract:

Ovarian cancer is immunogenic and residual tumor volume after surgery is known to be prognostic. Ovarian cancer often follows a recurring-remitting course and microscopic disease states may present ideal opportunities for immune therapies. We sought to establish the immune profile of a murine model of ovarian cancer that allows in vivo tumor imaging and the quantitation of microscopic disease.