Pregnancy, microchimerism, and the maternal grandmother.

Publication Type:

Journal Article

Source:

PloS one, Volume 6, Issue 8, p.e24101 (2011)

Keywords:

2011, Adult, Case-Control Studies, Center-Authored Paper, Child, Chimerism, Clinical Research Division, Female, Humans, Longitudinal Studies, Mothers, October 2011, Pre-Eclampsia, PREGNANCY, Research Trials Office Core Facility - Biostatistics Service, Shared Resources

Abstract:

A WOMAN OF REPRODUCTIVE AGE OFTEN HARBORS A SMALL NUMBER OF FOREIGN CELLS, REFERRED TO AS MICROCHIMERISM: a preexisting population of cells acquired during fetal life from her own mother, and newly acquired populations from her pregnancies. An intriguing question is whether the population of cells from her own mother can influence either maternal health during pregnancy and/or the next generation (grandchildren).