Prediction of individual genetic risk to prostate cancer using a polygenic score.

Publication Type:

Journal Article

Source:

The Prostate (2015)

Abstract:

Polygenic risk scores comprising established susceptibility variants have shown to be informative classifiers for several complex diseases including prostate cancer. For prostate cancer it is unknown if inclusion of genetic markers that have so far not been associated with prostate cancer risk at a genome-wide significant level will improve disease prediction.