Prediagnostic non-steroidal anti-inflammatory drug use and survival after diagnosis of colorectal cancer.

Publication Type:

Journal Article


Gut, Volume 60, Issue 4, p.491-8 (2011)


2011, Adult, Aged, Anti-Inflammatory Agents, Non-Steroidal, Aspirin, Colorectal Neoplasms, Drug Administration Schedule, Epidemiologic Methods, Female, Humans, Ibuprofen, Male, Middle Aged, Public Health Sciences Division, Washington, Young Adult


Non-steroidal anti-inflammatory drug (NSAID) use decreases both the incidence of colorectal cancer and recurrence of adenomas among patients with prior colorectal neoplasia. However, few studies have investigated the association between NSAID use and colorectal cancer-specific survival. The role of prediagnostic NSAID use was therefore examined in relation to colorectal cancer-specific survival among cases from the Seattle Colon Cancer Family Registry (Seattle Colon CFR).