Postmenopausal estrogen and progestin effects on the serum proteome.

Publication Type:

Journal Article


Genome medicine, Volume 1, Issue 12, p.121 (2009)


2009, Center-Authored Paper, Proteomics Core Facility, Public Health Sciences Division, Shared Resources, Specimen Processing Core Facility


Women's Health Initiative randomized trials of postmenopausal hormone therapy reported intervention effects on several clinical outcomes, with some important differences between estrogen alone and estrogen plus progestin. The biologic mechanisms underlying these effects, and these differences, have yet to be fully elucidated.