Polymorphisms in oxidative stress and inflammation pathway genes, low-dose ionizing radiation, and the risk of breast cancer among US radiologic technologists.

Publication Type:

Journal Article


Cancer causes & control : CCC, Volume 21, Issue 11, p.1857-66 (2010)


2010, Allied Health Personnel, Breast Neoplasms, Case-Control Studies, Center-Authored Paper, Chronic Disease, Cohort Studies, Cyclooxygenase 2, Dose-Response Relationship, Radiation, Female, Genotype, Humans, INFLAMMATION, Neoplasms, Radiation-Induced, Occupational Diseases, OXIDATIVE STRESS, Polymorphism, Genetic, Polymorphism, Single Nucleotide, Public Health Sciences Division, Radiation, Ionizing, RISK, Technology, Radiologic


Ionizing radiation, an established breast cancer risk factor, has been shown to induce oxidative damage and chronic inflammation. Polymorphic variation in oxidative stress and inflammatory-mediated pathway genes may modify radiation-related breast cancer risk.