Phase III randomized placebo-controlled trial of two doses of megestrol acetate as treatment for menopausal symptoms in women with breast cancer: Southwest Oncology Group Study 9626.

Publication Type:

Journal Article


Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 26, Issue 10, p.1650-6 (2008)


2008, Aged, Antineoplastic Agents, Hormonal, Breast Neoplasms, Female, Hot Flashes, Humans, Megestrol Acetate, Menopause, Middle Aged, Placebos, Public Health Sciences Division, Tamoxifen


Prior progestin studies treating hot flashes in women have been short duration and single dose. This study tests the progestin megestrol acetate (MA) at two doses versus placebo over 6 months.