Persisting with prevention: the importance of adherence for HIV prevention.

Publication Type:

Journal Article


Emerging themes in epidemiology, Volume 5, p.8 (2008)


2008, Center-Authored Paper, Epidemiology Core Facility, Shared Resources, Vaccine and Infectious Disease Institute


Only four out of 31 completed randomized controlled trials (RCTs) of HIV prevention strategies against sexual transmission have shown significant efficacy. Poor adherence may have contributed to the lack of effect in some of these trials. In this paper we explore the impact of various levels of adherence on measured efficacy within an RCT.