Performance of swabs, lavage, and diluents to quantify biomarkers of female genital tract soluble mucosal mediators.

Publication Type:

Journal Article

Source:

PloS one, Volume 6, Issue 8, p.e23136 (2011)

Keywords:

2011, Center-Authored Paper, September 2011, Vaccine and Infectious Disease Division

Abstract:

Measurement of immune mediators and antimicrobial activity in female genital tract secretions may provide biomarkers predictive of risk for HIV-1 acquisition and surrogate markers of microbicide safety. However, optimal methods for sample collection do not exist. This study compared collection methods.