The performance of prostate specific antigen for predicting prostate cancer is maintained after a prior negative prostate biopsy.

Publication Type:

Journal Article

Source:

The Journal of urology, Volume 180, Issue 2, p.544-7 (2008)

Keywords:

2008, Aged, Aged, 80 and over, Biopsy, Needle, Confidence Intervals, Digital Rectal Examination, Humans, Immunohistochemistry, Male, Mass Screening, Middle Aged, Predictive Value of Tests, Prognosis, Prostate-Specific Antigen, Prostatic Neoplasms, Public Health Sciences Division, Risk Assessment, ROC Curve, Statistics, Nonparametric, Survival Analysis, Tumor Markers, Biological

Abstract:

It has been suggested that prostate specific antigen has no predictive value for prostate cancer after a first negative biopsy has been performed. We compared the performance operating characteristics of prostate specific antigen for prostate cancer between a first and subsequent prostate biopsy in a group of men with complete verification of cancer status.