Optimizing viable leukocyte sampling from the female genital tract for clinical trials: an international multi-site study.

Publication Type:

Journal Article

Source:

PloS one, Volume 9, Issue 1, p.e85675 (2014)

Keywords:

2014, Center-Authored Paper, February 2014, Flow Cytometry Core Facility, Vaccine and Infectious Disease Division

Abstract:

Functional analysis of mononuclear leukocytes in the female genital mucosa is essential for understanding the immunologic effects of HIV vaccines and microbicides at the site of HIV exposure. However, the best female genital tract sampling technique is unclear.