Oophorectomy, hormone therapy, and subclinical coronary artery disease in women with hysterectomy: the Women's Health Initiative coronary artery calcium study.

Publication Type:

Journal Article


Menopause (New York, N.Y.), Volume 15, Issue 4 Pt 1, p.639-47 (2008)


2008, Aged, Calcinosis, Center-Authored Paper, Coronary Angiography, Coronary Artery Disease, Coronary Vessels, Estrogen Replacement Therapy, Estrogens, Conjugated (USP), Female, Humans, Hysterectomy, Middle Aged, Ovariectomy, Prevention Center Core Facility, Public Health Sciences Division, Randomized Controlled Trials as Topic, Risk Factors, Shared Resources, Tomography, X-Ray Computed


Surgical menopause has been associated with an increased risk of coronary heart disease events. In this study, we aimed to determine the associations between coronary artery calcium (CAC) and hysterectomy, oophorectomy, and hormone therapy use with a focus on the duration of menopause for which there was no hormone therapy use.