The nucleus inside out--through a rod darkly.

Publication Type:

Journal Article


Cell, Volume 137, Issue 2, p.205-7 (2009)


2009, Animals, Basic Sciences Division, Cell Nucleus, Euchromatin, HETEROCHROMATIN, MICE, Retinal Rod Photoreceptor Cells, Vision, Ocular


In the nuclei of eukaryotic cells, euchromatin is located at the center, whereas heterochromatin is found at the periphery and is interspersed in the nucleoplasm. Solovei et al. (2009) now reveal that this normal pattern is reversed in the retinal rod cells of mice. This inversion might serve to maximize light transmission to photoreceptors in nocturnal mammals.