Nonmyeloablative allogeneic hematopoietic cell transplantation in patients with acute myeloid leukemia.

Publication Type:

Journal Article

Source:

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 28, Issue 17, p.2859-67 (2010)

Keywords:

2010, Adolescent, Adult, Aged, Center-Authored Paper, Child, Child, Preschool, Clinical Research Division, Disease-Free Survival, hematopoietic stem cell transplantation, Humans, Leukemia, Myeloid, Acute, Male, Middle Aged, Prognosis, Research Trials Office Core Facility - Biostatistics Service, Shared Resources, Transplantation Conditioning, Treatment Outcome, Young Adult

Abstract:

Allogeneic hematopoietic cell transplantation (HCT) after high-dose conditioning regimens imposes prohibitively high risks of morbidity and mortality for patients with high-risk acute myeloid leukemia (AML) who are older or have comorbid conditions. Here, we examined outcomes after nonmyeloablative allogeneic HCT in such patients.