A non-human primate model for analysis of safety, persistence, and function of adoptively transferred T cells.

Publication Type:

Journal Article


Journal of medical primatology, Volume 40, Issue 2, p.88-103 (2011)


2011, Animals, Antigens, CD19, Antigens, CD20, CD8-Positive T-Lymphocytes, Cell Culture Techniques, Cell Movement, Cell Survival, Cells, Cultured, Clinical Research Division, CYTOMEGALOVIRUS, Cytomegalovirus Infections, Immunologic Memory, Immunotherapy, Adoptive, Macaca nemestrina, Models, Animal, Neoplasms, Polymerase Chain Reaction


Adoptive immunotherapy with antigen-specific effector T-cell (T(E) ) clones is often limited by poor survival of the transferred cells. We describe here a Macaca nemestrina model for studying transfer of T-cell immunity.