No reduction in C-reactive protein following a 12-month randomized controlled trial of exercise in men and women.

Publication Type:

Journal Article


Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Volume 17, Issue 7, p.1714-8 (2008)


2008, Adult, Aged, Body Weight, C-Reactive Protein, Center-Authored Paper, Colonic Neoplasms, Exercise, Exercise Test, Female, Follow-Up Studies, Humans, Incidence, Male, Middle Aged, Prevention Center Core Facility, Prognosis, Public Health Sciences Division, Retrospective Studies, Risk Factors, Shared Resources, Time Factors, Tumor Markers, Biological, United States


Low-grade systemic inflammation is suggested to play a role in the development of several chronic diseases including cancer. Higher levels of physical activity and lower adiposity have been associated with reduced levels of markers of systemic inflammation, such as C-reactive protein (CRP); however, reductions in CRP have not been consistently observed in randomized controlled trials of exercise.