No effect of aspirin on mammographic density in a randomized controlled clinical trial.

Publication Type:

Journal Article

Authors:

McTiernan, Anne; Wang, Ching-Yun; Sorensen, Bess; Xiao, Liren; Buist, Diana S M; Aiello Bowles, Erin J; White, Emily; Rossing, Mary Anne; Potter, John D; Urban, Nicole

Source:

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Volume 18, Issue 5, p.1524-30 (2009)

Keywords:

2009, Aged, Aspirin, Breast Neoplasms, Center-Authored Paper, Double-Blind Method, Female, Humans, Linear Models, Mammography, Middle Aged, Postmenopause, Prevention Center Core Facility, Public Health Sciences Division, Risk Factors, Shared Resources

Abstract:

Epidemiologic studies suggest a reduced risk of breast cancer among women who regularly use aspirin; a plausible mechanism is through aspirin effect on mammographic breast density, a breast cancer risk factor, possibly mediated through aspirin interference with estrogen synthesis.