New-onset breast tenderness after initiation of estrogen plus progestin therapy and breast cancer risk.

Publication Type:

Journal Article

Authors:

Crandall, Carolyn J; Aragaki, Aaron K; Chlebowski, Rowan T; McTiernan, Anne; Anderson, Garnet; Hendrix, Susan L; Cochrane, Barbara B; Kuller, Lewis H; Cauley, Jane A

Source:

Archives of internal medicine, Volume 169, Issue 18, p.1684-91 (2009)

Keywords:

2009, Aged, Breast, Breast Neoplasms, Center-Authored Paper, Estrogen Replacement Therapy, Estrogens, Conjugated (USP), Female, Humans, Medroxyprogesterone Acetate, Middle Aged, Pain, Postmenopause, Proportional Hazards Models, Public Health Sciences Division, Sensitivity and Specificity

Abstract:

Estrogen plus progestin therapy increases breast cancer incidence and breast tenderness. Whether breast tenderness during estrogen plus progestin therapy is associated with breast cancer risk is uncertain.