Mortality risk of black women and white women with invasive breast cancer by hormone receptors, HER2, and p53 status.

Publication Type:

Journal Article

Source:

BMC cancer, Volume 13, p.225 (2013)

Keywords:

2013, May 2013, Public Health Sciences Division

Abstract:

Black women are more likely than white women to have an aggressive subtype of breast cancer that is associated with higher mortality and this may contribute to the observed black-white difference in mortality. However, few studies have investigated the black-white disparity in mortality risk stratified by breast cancer subtype, defined by estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) status. Furthermore, it is not known whether additional consideration of p53 protein status influences black-white differences in mortality risk observed when considering subtypes defined by ER, PR and HER2 status.