Mitochondria and tumor progression in ulcerative colitis.

Publication Type:

Journal Article

Source:

Journal of the National Cancer Institute, Volume 105, Issue 16, p.1239-48 (2013)

Keywords:

2013, August 2013, Public Health Sciences Division

Abstract:

The role of mitochondria in cancer is poorly understood. Ulcerative colitis (UC) is an inflammatory bowel disease that predisposes to colorectal cancer and is an excellent model to study tumor progression. Our goal was to characterize mitochondrial alterations in UC tumorigenesis.