Methylation analysis in spontaneous sputum for lung cancer diagnosis.

Publication Type:

Journal Article


Lung cancer (Amsterdam, Netherlands) (2014)


2014, March 2014, Public Health Sciences Division


Lung cancer is the most fatal cancer in the developed world due to presence of metastases at time of diagnosis. The aim of this study is to examine DNA hypermethylation in sputum compared to sputum cytology for the diagnosis of lung cancer. A novel risk analysis is introduced, using the distinction between diagnostic and risk markers.