Menopausal symptom experience before and after stopping estrogen therapy in the Women's Health Initiative randomized, placebo-controlled trial.

Publication Type:

Journal Article


Menopause (New York, N.Y.), Volume 17, Issue 5, p.946-54 (2010)


2010, Center-Authored Paper, Drug Administration Schedule, Estrogen Replacement Therapy, Estrogens, Conjugated (USP), Female, Hot Flashes, Humans, Menopause, Placebos, Public Health Sciences Division


The aim of this study was to assess vasomotor and other menopausal symptoms before starting estrogens or placebo, 1 year later, again at trial closure, and after stopping estrogens or placebo. The role of baseline symptoms and age was examined, as was the frequency and determinants of hormone use and symptom management strategies after discontinuing conjugated equine estrogens (CEE) or placebo.