Intraoperative radio-lympho-scintigraphy improves sentinel lymph node identification for patients with melanoma.

Publication Type:

Journal Article


Annals of surgery, Volume 223, Issue 2, p.217-24 (1996)


Adolescent, Adult, Aged, Aged, 80 and over, Binomial Distribution, Biopsy, Female, Humans, Intraoperative Care, Lymph Node Excision, Lymph Nodes, Lymphatic Metastasis, Male, MELANOMA, Middle Aged, Rosaniline Dyes, Skin Neoplasms, Technetium Tc 99m Sulfur Colloid


The sentinel lymph node (SLN), the first node draining the primary tumor site, has been shown to reflect the histologic features of the remainder of the lymphatic basin in patients with melanoma. Intraoperative localization of the SLN, first proposed by Morton and colleagues, has been accomplished with the use of a vital blue dye mapping technique. Technical difficulties resulting in unsuccessful explorations have occurred in up to 20% of the dissections.