International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways.

Publication Type:

Journal Article

Source:

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Volume 17, Issue 11, p.3081-9 (2008)

Keywords:

2008, Adult, Aged, Aged, 80 and over, Cell Cycle Proteins, DNA repair, DNA-Binding Proteins, Female, Genetic Variation, Genome-Wide Association Study, Humans, Lung Neoplasms, Male, Middle Aged, Public Health Sciences Division

Abstract:

The International Lung Cancer Consortium was established in 2004. To clarify the role of DNA repair genes in lung cancer susceptibility, we conducted a pooled analysis of genetic variants in DNA repair pathways, whose associations have been investigated by at least 3 individual studies.