Insulin-like growth factor-I, insulin-like growth factor binding protein-3 and risk of benign prostate hyperplasia in the prostate cancer prevention trial.

Publication Type:

Journal Article


The Prostate, Volume 68, Issue 13, p.1477-86 (2008)


2008, Aged, Aged, 80 and over, Biological Markers, Body Mass Index, Case-Control Studies, Humans, Insulin-Like Growth Factor Binding Proteins, Insulin-Like Growth Factor I, Life Style, Logistic Models, Male, Middle Aged, Predictive Value of Tests, Prostatic Hyperplasia, Prostatic Neoplasms, Public Health Sciences Division, Risk Factors


We investigated whether peptides involved in cellular proliferation and apoptosis, [insulin-like growth factor I (IGFI) and its major binding protein (insulin-like growth factor binding protein 3)], predicted risk of benign prostate hyperplasia (BPH).