HIV-1 persists in breast milk cells despite antiretroviral treatment to prevent mother-to-child transmission.

Publication Type:

Journal Article

Source:

AIDS (London, England), Volume 22, Issue 12, p.1475-85 (2008)

Keywords:

2008, Adult, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Cell-Free System, DNA, Viral, Drug Therapy, Combination, Female, HIV Infections, HIV-1, Human Biology Division, Humans, Infectious Disease Transmission, Vertical, Milk, Human, Nevirapine, Postpartum Period, Public Health Sciences Division, RNA, Viral, Time Factors, Treatment Outcome, Viral Load, Zidovudine

Abstract:

The effects of short-course antiretrovirals given to reduce mother-to-child transmission (MTCT) on temporal patterns of cell-associated HIV-1 RNA and DNA in breast milk are not well defined.