High expression of the very late antigen-4 integrin independently predicts reduced risk of relapse and improved outcome in pediatric acute myeloid leukemia: a report from the children's oncology group.

Publication Type:

Journal Article

Authors:

Walter, Roland B; Alonzo, Todd A; Gerbing, Robert B; Ho, Phoenix A; Smith, Franklin O; Raimondi, Susana C; Hirsch, Betsy A; Gamis, Alan S; Franklin, Janet L; Hurwitz, Craig A; Loken, Michael R; Meshinchi, Soheil

Source:

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 28, Issue 17, p.2831-8 (2010)

Keywords:

2010, Adolescent, Adult, Age Factors, Center-Authored Paper, Child, Child, Preschool, Clinical Research Division, Clinical Trials, Phase III as Topic, Cohort Studies, Flow Cytometry Core Facility, Humans, Infant, Integrin alpha4beta1, Leukemia, Myeloid, Acute, Male, Prognosis, Prospective Studies, Treatment Outcome, Young Adult

Abstract:

To evaluate the prognostic significance of the integrin cell adhesion molecule very late antigen-4 (VLA-4) in acute myeloid leukemia (AML).