Hematopoietic cell transplantation after nonmyeloablative conditioning for advanced chronic lymphocytic leukemia.

Publication Type:

Journal Article

Source:

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 23, Issue 16, p.3819-29 (2005)

Keywords:

Adult, Aged, Antineoplastic Agents, Combined Modality Therapy, Disease-Free Survival, Female, Graft vs Leukemia Effect, hematopoietic stem cell transplantation, Humans, Leukemia, Lymphocytic, Chronic, B-Cell, Male, Middle Aged, Neoplasm Recurrence, Local, Remission Induction, Salvage Therapy, Survival Rate, Transplantation Conditioning, Transplantation, Autologous, Vidarabine, Whole-Body Irradiation

Abstract:

Patients with chemotherapy-refractory chronic lymphocytic leukemia (CLL) have a short life expectancy. The aim of this study was to analyze the outcome of patients with advanced CLL when treated with nonmyeloablative conditioning and hematopoietic cell transplantation (HCT).