Health outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy: a randomized controlled trial.

Publication Type:

Journal Article


JAMA : the journal of the American Medical Association, Volume 305, Issue 13, p.1305-14 (2011)


2011, Aged, Breast Neoplasms, Colorectal Neoplasms, Coronary Disease, Double-Blind Method, Estrogen Replacement Therapy, Estrogens, Estrogens, Conjugated (USP), Female, Follow-Up Studies, Hip Fractures, Humans, Hysterectomy, Middle Aged, Outcome Assessment (Health Care), Postmenopause, Public Health Sciences Division, RISK, Stroke, Venous Thrombosis


The Women's Health Initiative Estrogen-Alone Trial was stopped early after a mean of 7.1 years of follow-up because of an increased risk of stroke and little likelihood of altering the balance of risk to benefit by the planned trial termination date. Postintervention health outcomes have not been reported.