Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy.

Publication Type:

Journal Article


Sexually transmitted infections, Volume 87, Issue 2, p.114-7 (2011)


2011, Adult, Anti-HIV Agents, Cervix Uteri, Female, HIV Infections, HIV-1, Human Biology Division, Humans, Mucus, Prospective Studies, Public Health Sciences Division, RNA, Viral, Ulcer, Uterine Cervical Diseases, Vagina, Vaginal Diseases, Virus Shedding


Genital ulcer disease (GUD) is associated with increased HIV-1-RNA shedding in antiretroviral therapy (ART)-naive women. The effect of GUD on HIV-1 shedding among ART-treated women is not known. The objective of this study was to test the hypothesis that genital ulcerations increase genital HIV-1-RNA shedding in women receiving ART.