Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy.

Publication Type:

Journal Article

Source:

Sexually transmitted infections, Volume 87, Issue 2, p.114-7 (2011)

Keywords:

2011, Adult, Anti-HIV Agents, Cervix Uteri, Female, HIV Infections, HIV-1, Human Biology Division, Humans, Mucus, Prospective Studies, Public Health Sciences Division, RNA, Viral, Ulcer, Uterine Cervical Diseases, Vagina, Vaginal Diseases, Virus Shedding

Abstract:

Genital ulcer disease (GUD) is associated with increased HIV-1-RNA shedding in antiretroviral therapy (ART)-naive women. The effect of GUD on HIV-1 shedding among ART-treated women is not known. The objective of this study was to test the hypothesis that genital ulcerations increase genital HIV-1-RNA shedding in women receiving ART.