Genetic Variations in SMAD7 Are Associated with Colorectal Cancer Risk in the Colon Cancer Family Registry.

Publication Type:

Journal Article

Source:

PloS one, Volume 8, Issue 4, p.e60464 (2013)

Keywords:

2013, April 2013, Center-Authored Paper, Epidemiology Core Facility, Public Health Sciences Division, Specimen Processing Core Facility

Abstract:

Recent genome-wide studies identified a risk locus for colorectal cancer at 18q21, which maps to the SMAD7 gene. Our objective was to confirm the association between SMAD7 SNPs and colorectal cancer risk in the multi-center Colon Cancer Family Registry.