Factors Associated with Physical Activity Among Adolescent and Young Adult Survivors of Early Childhood Cancer: A report from the Childhood Cancer Survivor Study (CCSS).

Publication Type:

Journal Article


Psycho-oncology (2017)


OBJECTIVE: To evaluate concurrent and longitudinal associations between psychosocial functioning and physical activity in adolescent and young adult survivors of early childhood cancer.

METHODS: Adolescent survivors of early childhood cancer (diagnosed before age four) participating in the Childhood Cancer Survivor Study completed the Coping Health and Illness Profile-Adolescent Edition (CHIP-AE; n=303; mean age at survey 17.6 years). A subset of these survivors (n=248) completed a follow-up survey an average of 6.0 years later (range: 4-10). Logistic regression identified associations between psychosocial functioning in adolescence and physical activity levels in adolescence and young adulthood.

RESULTS: Survivors reported low physical activity as adolescents (46.1% scored below CHIP-AE cut-point) and young adults (40.8% below CDC guidelines). Poor physical activity during adolescence was associated with female sex (OR=2.06, 95%CI=1.18-3.68), parents with less than a college education (OR=1.91, 95%CI 1.11-3.32), previous treatment with cranial radiation (OR=3.35, 95%CI=1.69-6.88), TV time (OR=1.77, 95%CI=1.00-3.14), and limitations of activity due to health or mobility restrictions (OR=8.28, 95%CI=2.87-30.34). Poor diet (OR=1.84, 95%CI=1.05-3.26) and low self-esteem (OR=1.80, 95%CI=0.99-3.31) during adolescence were associated with lower odds of meeting CDC physical activity guidelines in young adulthood.

CONCLUSION: These findings provide targets for future interventional studies to improve physical activity in this high-risk population.