Evidence-based use of colony-stimulating factors in elderly cancer patients.

Publication Type:

Journal Article


Cancer control : journal of the Moffitt Cancer Center, Volume 10, Issue 6, p.487-99 (2003)


Aged, Antineoplastic Combined Chemotherapy Protocols, Colony-Stimulating Factors, Decision Trees, Evidence-Based Medicine, Hospital Costs, Humans, Neoplasms, NEUTROPENIA, United States


Neutropenia and its complications represent the major dose-limiting toxicity of cancer chemotherapy, especially in the elderly. Hematopoietic growth factors have been shown to reduce the severity and duration of febrile neutropenia (FN) and to sustain chemotherapy dose intensity.