Evaluation of early discharge after hospital treatment of neutropenic fever in acute myeloid leukemia (AML).

Publication Type:

Journal Article


Leukemia research reports, Volume 2, Issue 1, p.26-8 (2013)


2013, Clinical Research Division, January 2014


Hospital admission for neutropenic fever in patients with AML is a standard practice. However, discharge practices vary once patients become afebrile, with many patients hospitalized until rise in the absolute neutrophil count (ANC) to >500 (ANC recovery). Data to support this practice are sparse. We hypothesized that patients admitted for neutropenic fever, particularly if in complete remission (CR) or about to enter CR following the chemotherapy course associated with neutropenic fever, might be safely discharged earlier (ED). Benefits of ED are less exposure to hospital pathogens, reduced cost, increased availability of beds for patients more in need of urgent care, and potentially, enhanced psychological well-being.